If you have a logic analyzer or oscilloscope, check HS2 for the clock (available on the unpopulated 10-pin header next to the 20-pin connector).
Other things to check:
- are you sure your USB cable is good?
- reduce baud rate as explained in this post
- is your VM USB controller set to USB 3.0?
- can you try running natively, instead of VM?
Also I’m assuming that Setup_Generic.ipynb is running cleanly without any errors?
Jean-Pierre