I have a 5V target circuit and I use a 74LVC1G07 (Single driver with open collector output) to regulate down the signal I intend to use as a trigger. I use a pull-up resistor to the 3.3V coming from the target’s USB chip. When measured, it isn’t 3.3V but 3.6V. It would be smarter to connect the pull up resistor to the 3.3V coming from the ChipWhisperer Lite, but…
I believe ChipWhisperer Lite will tolerate 3.6V and even very close to 4.0V. What do your say?
BTW: Are the 5V pins connected to anything at all?